Vol. 5, Issue 1, Part A (2023)

Background: Platelet rich plasma (PRP) is a promising and novel therapy for the treatment of androgenetic alopecia. There are various growth factors in PRP which induce the proliferation of dermal papilla cells. Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma. Although the optimal PRP platelet concentration is unclear, the current methods by which There has been a lot of hype on the use of platelet rich plasma (PRP) for various dermatological indications including acne scarring, leg ulcers, facial rejuvenation, alopecia areata and androgenetic alopecia. Out of all the treatment modalities, platelet rich plasma shows promising results.

Objective: To assess the platelet-rich plasma therapy for hair loss treatment in North Bengal Medical College, Sirajganj, Bangladesh.

Methods: A randomised controlled trial was conducted in Dept. Of Dermatology, North Bengal Medical College, Sirajganj, Bangladesh from January 2020 to December 2022, on the efficacy of platelet rich plasma in 100 patients with patterned hair loss. We selected a hundred cases of both male and female pattern hair loss for the study. Written informed consent of all the patients was taken before the start of the study.

Results: A total of 100 patients were included in our study. There were 84 males and 16 females and male: female was 5.2:1. Maximum number of patients (68%) were between 31 to 60 years of age, followed by 32 (32%) patients between 21 to 30 years of age. Very good improvement was seen in 32 (32%) patients, good improvement was seen in 48 (48%) patients, average improvement, was seen in 8 (8%) and poor improvement, was seen in 12 (12%) patients. Regarding the side effects of PRP, bruising was seen in 8 (8%), pain was seen in 12 (12%). After 4 months of treatment, average hair count increased by 40% and average hair shaft diameter increased by 56%.

Conclusions: PRP is a novel therapy, but is not an evidence-based therapy for the treatment of alopecia.